A  Real  Age  Killing  Effect

Tripeptide (SYN®- AKE) is a  anti-wrinkle  active  compound  based on a  tripeptide, that  mimics   the   activity   of  Waglerin 1,  a  polypeptide  that  is  found  in  the  venom  of  the  temple viper. Clinical  trials  have shown  that  Tripeptide   (SYN® - AKE) is  capable  of  reducing  mimic wrinkles by  inhibiting muscle contractions, smoothing mimic wrinkles in a short period, and is reversible. Tripeptide (SYN®- AKE)  is  useful  in  anti-aging   products   and   wrinkle  treatment  products, especially those targeting expression lines. While the actual venom paralyzes, this peptide   copies   only    the   component   which   relaxes   the   muscles (Waglerin 1). Pentapharm postulates that  acts  similarly  to  Argireline by  interfering  with  the  transmission  of  nerve  signals to the muscles directing them to contract.

Tripeptide (SYN® - AKE)

                                                                                                                                                                                                                                                    The Technology Mimic wrinkles are part of the visible face wrinkles. As time passes, these wrinkles persist permanently and get deeper and deeper: frown lines, laughter lines and crows feet line appear more  and  more  due  to  the  repeated  movements  of  facial  muscles. Tripeptide (SYN® - AKE) has  been developed as efficient smoothing  and  anti-wrinkle  care  particularly effective against expression lines by relaxing facial muscles. This active tripeptide acts in a manner similar to Walglerin 1, a  neuromuscular  blocking  compound  of  the  venom  of  the  temple viper. Acting at the post-synaptic membrane, Tripeptide (SYN® - AKE) is a reversible  antagonist of  the  muscular  nicotinic  acetylcholine  receptor (mnAChR).





We assume that the tripeptide is binding to the receptor; consequently it remains closed. In the closed state, sodium ions (Na+) are not released and the muscles stay relaxed.  Apple Stem Cell Anti-aging Facial.