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“Swiss Apple Stem Cell“

PhytoCellTec™ Malus Domestica is a liposomal preparation of apple stem cells developed by a novel, patent pending plant cell culture technology.PhytoCellTec™ - a novel plant cell culture technology has been invented to cultivate dedifferentiated callus cells from a rare Swiss apple.


These apple stem cells are rich in epigenetic factors and metabolites, assuring the longevity of skin cells. PhytoCellTec™ Malus Domestica has been shown to protect skin stem cells and delay the senescence of hair follicles. PhytoCellTec™ Malus Domestica provides a revolutionary anti-aging performance for real rejuvenation.


Claims with PhytoCellTec™ Malus Domestica

• Protects longevity of skin stem cells

• Delays senescence of essential cells

• Combats chronological aging

What is PhytoCellTech Malus Domestica

PhytoCellTec™ Malus Domestica is a liposomal active ingredient based on stem cells from the Uttwiler Spätlauber apple.


The apple

The Uttwiler Spätlauber is an old Swiss variety, which is very rare today. It was known for its exceptional capacity to keep for long periods but gradually lost its popularity to sweet apples because of its bitter taste. As the apple could be stored for a long time without becoming shriveled or losing flavor, it clearly had special ingredients and especially long-lived stem cells. And precisely these longevity factors were of particular interest to the researchers at Mibelle Biochemistry. Despite its long shelf-life, the apple has not been considered desirable until now because of its tart taste. Consequently the number of trees has rapidly dwindled. The variety, first recorded in the mid-18th century, comes from northern Switzerland. If the tree's bark or the skin of an unpicked fruit is punctured it heals. And once picked, an Uttwiler Spätlauber apple lasts months longer than its shrivelled cousins.


At present there are only 20 Uttwiller Spätlauber trees in Switzerland. They belong to ProSpecieRara, a foundation aiming to preserve traditional breeds of animals and plants in Switzerland. The organisation has managed to preserve 1,800 varieties on 8,000 trees during its 25 years in operation, through collecting samples, growing them and then distributing them to people willing to look after them. Bela Bartha, foundation director, said: "We have undiscovered treasures in these collections."


Plant stem cells for skin stem cells

Swiss scientists at Mibelle Biochemistry, which is a subsidiary of the big Swiss retailer Migros, decided to investigate whether the miracle component could be harnessed to stop the ageing process in people. They found the key to the apple's longevity lay chiefly in its unusually resilient stem cells. In clinical tests the apple's stem cells appeared to be protecting human stem cells. They nourished and stimulated them and defended them against UV radiation. The development of the innovative PhytoCellTec™ technology made possible to grow plant stem cells on a large scale. It also became possible to effectively cultivate rare and endangered plants like the Uttwiler Spätlauber. PhytoCellTec™ made plant stem cells available for cosmetics for the first time.


The effect;

Mibelle Biochemistry was able to show in comprehensive studies that PhytoCellTec™ Malus Domestica, the active ingredient based on apple stem cells, promotes the vitality and longevity of skin stem cells, protects them from damage due to environmental stress and thus delays the skin aging processes. They made a cream containing a two percent Uttwiler Spätlauber extract and applied it twice daily to the "crow's feet" area under the eyes of 20 participants. Wrinkle depth was reduced by an average of 15 per cent after four weeks. "We could show that the apple stem cells have a positive influence on the vitality of the skin stem cells. They made them more efficient and they can live longer".



PhytoCellTec™ Malus Domestica has opened up entirely new possibilities in the field of cosmetics. Using plant stem cells can slow skin aging by protecting essential skin stem cells, keeping the skin looking youthful longer, and giving it a better and more vital appearance.



Improves the vitality of stem cells Cultures of epidermal stem cells were treated with different concentrations of PhytoCellTec™ Malus Domestica and their colony-forming efficiency was determined. The investigations showed that PhytoCellTec™ Malus Domestica had a clear, positive effect on stem cell characteristics. Preserves the ability to form new epidermal tissueYoung, vital epidermal stem cells can form a complete, multi-layer epidermis in laboratory conditions.When this experiment is conducted on older stem cells, these no longer multiply and no epidermis is formed. These stem cells are depleted and have reached the end of their lifecycle. If, however, Malus Domestica stem cell extract is added to cultivate the stem cells, even “old” stem cells can still generate a stratified epidermis. Under the influence of Malus Domestica stem cell extract, the epidermal stem cells retain their vitality longer and are capable of forming new tissue and renewing the skin.


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